Periodontitis bacteria no longer found in the mouth after 3-week treatment using Parx Plastics technology

Clinical experiments show that patients with periodontitis benefit significantly from wearing a dental tray by Zinkh NV, a Parx Plastics joint-venture.

Periodontal disease (gum infection) is the second most prevalent oral disease globally, affecting close to 50% of adults’ oral condition. Periodontitis is often linked to poor oral hygiene, and treatment at current consists of (repeated) professional deep cleaning, often combined with antibiotics. In severe cases, even surgery may be required.

Dr. Di Chiaro, clinical consultant at Zinkh NV says,

“The results we are seeing from the Zinkh trays are very exciting. A local zinc immune boost from this simple but unique tray is helping patients recover a lot faster than normal, with no need for antibiotics. On top, the tray helps prevent future inflammations, which is one of the big challenges with periodontal disease.”

Dr. Gianluca Di Chiaro has run different clinical experiments. Using a PerioPOC test, the presence of Periodontitis pathogens is detected before treatment. The treatment itself consists of a custom-made dental tray that is thermoformed from a specially prepared plate with the Parx technology inside. Patients wore a Zinkh dental tray overnight, for a period of 3 weeks, after which a new PerioPOC test was performed.

The PerioPOC test identifies the following 5 most relevant Periodontitis pathogens:

  • Td: Treponoma denticola

  • Tf : Tannerella forsythia

  • Pg: Porphyromonas gingivalis

  • Pi : Prevotella intermedia

  • Aa: Aggregatibacter actinomycetemcomitans  

    (C1, C2 and TGL are control values)


PerioPOC test results before treatment and after treatment. Tests performed by Dr. Gianluca Di Chiaro, a clinical and scientific consultant working for Zinkh NV, a Parx Plastics partner. (click image to zoom)

A reorganization of the tissues in the coronal direction around the implant surface was also found. (click image to zoom)


Patients undergoing this treatment show a significant reduction of the Periodontitis pathogens or show a complete absence of these strains. 

Dr. Di Chiaro comments,

“In just 3 weeks, a lowering of the bacterial load and a decrease in the bleeding indexes was evidenced. Around the implant a reorganization of the tissues was visible, which is extremely remarkable in such a short period of time.“

Antimicrobial and antibiofilm technology
Parx Plastics developed and patented a method to incorporate the trace element of Zinc in polymers. This innovative method using the second most abundant trace element in the human body creates a modified mechanical/physical surface property that makes the surface resistant to bacteria and biofilm formation. Bacteria are not able to adhere to the surface and do not proliferate on the surface which results in a 99.9% or higher antimicrobial performance measured according to international norm ISO 22916. The technology does not only use a biocompatible and non-toxic element, but the technology is also intrinsic in the material and generates the antimicrobial effect without migration. So without the use of any toxic substances and without any elements leaching from the surface makes it an unprecedented safe technology.

Zinkh oral bacterial management
Zinkh NV, a joint venture established January 2019 in Belgium, focusses on bringing the benefits of the trace element technology into the dental field. A combination of clinical as well as business development veterans in the dental industry, Zinkh’s management team is in a unique position to launch a revolution in bacteria management. By not only supplying existing appliances such as bruxism or orthodontic splints with anti-microbial properties, but also developing new proprietary appliances in the realm of periodontitis & implantology, Zinkh is looking to become the global leader in dental bacteria management solutions.

Parx Plastics